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C3.4(a) applies where protection is required to doorways, windows and other openings. C3.4(b) requires fire doors, fire windows and fire shutters to comply with Specification C3.4. C3.4 is referred to by a number of the BCA's Deemed-to-Satisfy Provisions. Some of these provisions will specify whether or not a required sprinkler system must be internal or external.
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2 Answers. It isn't. It is an ASCII description of the UTF-8 encoding. Since it is data encoded in a URL, use the urldecode function. First you need to urldecode it, this will give you ü, which is the UTF8-encoded representation of ü, so you should be all good.
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The third component of complement (C3) fulfills a pivotal role in the functions of the complement system. We have investigated the topological relationships among its polypeptide chains, physiologic fragments, enzyme attack regions, and functional sites. C3 consists of two chains (alpha and beta) which are linked by disulfide bonds and.
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Complement component C3: A structural perspective and potential therapeutic implications. 2022 Jan:59:101627. doi: 10.1016/j.smim.2022.101627. Epub 2022 Jun 25. As the most abundant component of the complement system, C3 and its proteolytic derivatives serve essential roles in the function of all three complement pathways.
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(b) Model of the enzyme-substrate complex (C3bBb-C3), constructed by superimposition of C3 (Protein Data Bank accession code 2A73) 32 on the MG4-MG5 domains of the dimeric C3b molecule in the.
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Figure 2. (A) An illustration of the newly developed assay to measure non-proteolytically activated C3.(B) Schematic linear representation of native C3 [α-chain alone with indicated cleavage sites for convertases and Factor I appointed 1-3 (top of the figure) and the intact C3 molecule with a mark for the position of the thioester (below)], non-proteolytically activated C3 i.e., C3(x) (left.
Specification C3.15 sets out details of permissible service penetrations through walls, floors and ceilings, and was developed using building practices that are in general use. The Specification permits the use of metal pipe systems and conduits (but not flue pipes) which do not satisfy the insulation criteria of AS 1530.4, provided certain criteria are met.
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The complement system is an integral part of the body's immune defenses. It can be activated via immune complexes (classic pathway) or by bacterial polysaccharides (alternative pathway).The primary complement pathway consists of recognition (Clq, Clr, Cls), activation (C4, C2, C3), and attack (C5, C6, C7, C8, C9) mechanisms with respect to their role in antibody-mediated cytolysis.
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To highlight the important role that C3 plays in human biological processes, we will give an overview of the diseases linked to C3 deficiency and to uncontrolled C3 activation. Next, we will present a structural description of C3 activation and of the C3 fragments generated by complement regulation.
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The final refined models had R and R free values of 22.3 and 27.9% (C3c) and 23.6 and 29.5% (C3); see Methods and Table 1; see also Supplementary Fig. 1 and Supplementary Table 1. Table 1.