Patent US20110195120 Sustained Release Pharmaceutical Composition Containing Metformin
1. Process for the preparation of metformin HCl comprising the steps (a) heating a mixture of dimethylammonium chloride, dicyanodiamide, water in an amount from 0 to 20% by weight and metformin HCl in an amount from 0 to 50% by weight, each based on the total weight of dimethylammonium chloride and dicyanodiamide present in the mixture, to a temperature in the range from 70° C. to 250° C.
Patent WO2007038979A1 Effervescent metformin composition and tablets and granules made
Nausea, vomiting, stomach upset, diarrhea, weakness, or a metallic taste in the mouth may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. If stomach.
Patent US20080274180 Extended Release Pharmaceutical Composition of Metformin and a Process
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WO2004110422A1 Extendedrelease tablets of metformin Google Patents
feeling dizzy, light-headed, tired, or very weak; stomach pain, vomiting; or. slow or irregular heart rate. Common metformin side effects may include: low blood sugar; nausea, upset stomach; or. diarrhea. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Patent US6866866 Controlled release metformin compositions Google Patents
1. WO2021012274 - PREPARATION METHOD FOR METFORMIN HYDROCHLORIDE. The present invention provides a preparation method for metformin hydrochloride. The preparation method comprises: heating raw materials comprising dicyandiamide and dimethylamine hydrochloride by means of microwave, and making the two react at 100-160°C to obtain a product.
Metformin 850 1 A Pharma® 120 St
Metformin oral tablet is a prescription drug that's used along with diet and exercise to treat high blood sugar levels caused by type 2 diabetes. Tablets are available as generic drugs and as.
Patent US7919116 Controlled release metformin formulations Google Patents
1. A tablet for oral administration comprising metformin hydrochloride, and further comprising from 0.05 to 0.5 part methylcellulose per part metformin hydrochloride by weight, wherein said tablet is free of stearate or further comprises less than 0.6% stearate by weight.
Patent US8581001 Metformincysteine prodrug Google Patents
Additional information is available in the individual branded drug profile pages. Metformin hydrochloride has fifty-six patent family members in sixteen countries. There are forty-three drug master file entries for metformin hydrochloride. Eighty-six suppliers are listed for this compound. There are four tentative approvals for this compound.
Patent US20110021634 Processes for preparing metformin hydrochloride Google Patents
This article aims to summarize metformin's anticancer effects through reviewing its literatures and patents, with a focus on its potential to be repurposed for cancer therapy. Various databases were examined using keywords, 'Metformin' and 'Cancer'. Research articles were collected through the PubMed database, clinical trials were obtained from.
WO2004110422A1 Extendedrelease tablets of metformin Google Patents
Metformin, an antidiabetic agent, was approved by the U.S. Food and Drug Administration (FDA) in 1994 for treating type 2 diabetes. This medication comes in both immediate- and extended-release formulations and is often combined with other antidiabetic agents. The off-label indications of metformin include managing gestational diabetes, addressing weight gain issues caused by antipsychotic.
Patent EP1945190A1 Effervescent metformin composition and tablets and granules made therefrom
Description. Metformin hydrochloride is an orally-administered antihyperglycemic agent, used in the management of non-insulin-dependent diabetes mellitus. Metformin hydrochloride tablets are sold in strengths of 500 mg, 850 mg and 1000 mg in the United States and elsewhere under the tradename Glucophage™.
Patent EP2498757A1 Reduced mass metformin formulations Google Patents
US 6,667,054 B2. 1. METFORMIN HYDROCHLORIDE TABLETS. BACKGROUND OF THE INVENTION. Metformin hydrochloride is an orally-administered anti hyperglycemic agent, used in the management of non insulin-dependent diabetes mellitus. Metformin hydrochloride tablets are sold in strengths of 500 mg, 850 mg and 1000 mg in the United States and elsewhere.
Metformin Tablet Uses And Side Effects Is Safe For Cancer Patients?
approximately 5%. To this mixture, 250 g of dicyanodiamide was added. The reactor is heated to 145°C for 3 hours. As the reaction proceeds, metformin hydrochloride precipitates from the mixture. The reactor is cooled to room temperature, demineralized water is added to the reactor and the resulting slurry is removed.
Patent US8475841 Controlled release metformin formulations Google Patents
The invention provides compositions and methods to treat diabetes with improved formulations in which metformin is combined with at least three antioxidants that contain a stabilizing heteroatom adjacent to a saturated carbon and which help maintain a balance between antioxidant and pro-oxidant properties. The antioxidants include at least the combination of taurine, citrulline and.
Patent US20120283332 Transdermal delivery of metformin Google Patents
The invention provides compositions and methods to treat diabetes with improved formulations in which metformin is combined with at least three antioxidants that contain a stabilizing heteroatom adjacent to a saturated carbon and which help maintain a balance between antioxidant and pro-oxidant properties. The antioxidants include at least the combination of taurine, citrulline and.
Patent WO2009099734A1 Pharmaceutical compositions of a combination of metformin and a
Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. It is sometimes used as an off-label adjunct to lessen the risk of metabolic syndrome in people who take antipsychotics.