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Indications and Dosage. Intravenous. Supraventricular arrhythmias, Ventricular arrhythmias. Adult: Initially, 5 mg/kg via infusion over a period of 20-120 minutes, may repeat infusion up to 1,200 mg (approx 15 mg/kg) per 24 hours, with a rate of infusion adjusted based on clinical response. For emergency cases: 150-300 mg via slow inj over ≥3.
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After the first 24 hours, the maintenance infusion rate of 0.5 mg/min (720 mg/24 hours) should be continued utilizing a concentration of 1 to 6 mg/mL (amiodarone HCl injection concentrations greater than 2 mg/mL should be administered via a central venous catheter).In the event of breakthrough episodes of VF or hemodynamically unstable VT, 150 mg supplemental infusions of amiodarone HCl.
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Adjustment dose: 600 to 800 mg orally per day for 1 month, then switch to maintenance dose. Maintenance dose: 400 mg orally per day. Comments: May be administered once a day; twice a day dosing is recommended for total daily doses of 1000 mg or more or in patients who experience gastrointestinal tolerance. Close monitoring is indicated during.
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Amiodarone :Antiarrhythmic Agent INDICATIONLife-threatening ventricular arrhythmiasventricular tachycardia ventricular fibrillation.-----.
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Side Effects for Cordarone IV. In a total of 1836 patients in controlled and uncontrolled clinical trials, 14% of patients received Cordarone I.V. for at least 1 week, 5% received it for at least 2 weeks, 2% received it for at least 3 weeks, and 1% received it for more than 3 weeks, without an increased incidence of severe adverse reactions.
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Lynne Kelly, Pharmacist, CCTC Brenda Morgan, Clinical Nurse Specialist, CCTC Last Update: September 21, 2020; Reviewed February 13, 2023 (BM)
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Dosis Amiodarone. Obat amiodarone digunakan pada pasien dewasa dengan rincian dosis sebagai berikut [1]: → Dosis awal 5 mg/kg melalui infus selama 20-120 menit, dapat diulang infus hingga 1.200 mg (sekitar 15 mg/kg) per 24 jam, dengan kecepatan infus disesuaikan berdasarkan respon klinis.
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Half-Life Elimination. Note: Half-life is shortened in children vs adults. Amiodarone: Single dose: 58 days (range: 15 to 142 days) Oral chronic therapy: Mean range: 40 to 55 days (range: 26 to 107 days) IV single dose: Mean range: 9 to 36 days. N-desethylamiodarone (active metabolite): Prolonged in severe left ventricular dysfunction.
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360 mg over the NEXT 6 hours (1 mg/min). Add 18 mL of amiodarone (900 mg) to 500 mL D 5 W (concentration = 1.8 mg/mL) Maintenance infusion. 540 mg over the REMAINING 18 hours (0.5 mg/min). Decrease the rate of the slow loading infusion to 0.5 mg/min. Table 2: AMIODARONE HYDROCHLORIDE SOLUTION STABILITY. Solution.
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Prescribe 900mg of amiodarone to be administered as a continuous infusion (ideally via a CVC). Dilute in a 500mL glucose 5% non-PVC fluid bag (free-flex bag. Available in ACC or the RHW AHDR). Administer via an infusion pump giving set over 24hours at a rate of 21mL/hour Follow with oral/IV dose as per Drs orders.
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Dewasa: awalnya, 200 mg sebanyak 3 kali sehari selama 1 minggu kemudian dikurangi menjadi 200 mg tiap dua hari selama seminggu lagi. Dosis pemeliharaan sebanyak 200 mg setiap hari berdasarkan respons pasien. Lansia: gunakan dosis efektif minimum. Dosis di atas hanyalah pedoman umum terkait penggunaan obat ini.
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92 AmiodArone HydrocHloride ASHP inJecTABle drUG inFormATion Amiodarone Hydrochloride AHFS 24:04.04.20 Products Amiodarone hydrochloride 50 mg/mL is available in 3-, 9-, and 18-mL vials. Each mL also contains polysorbate 80 100 mg, and
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INDICATIONS AND USAGE. Amiodarone injection is an antiarrhythmic agent indicated for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation (VF) and hemodynamically unstable ventricular tachycardia (VT) in patients refractory to other therapy. ( 1) DOSAGE AND ADMINISTRATION.
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Dosis awal 200 mg, 3 kali sehari, selama 1 Dosis selanjutnya dapat dikurangi menjadi 200 mg, 2 kali sehari. Dosis pemeliharaan bisa diturunkan tergantung pada respons tubuh pasien. Sementara itu, amiodarone bentuk suntik biasanya digunakan untuk gangguan irama jantung yang darurat, seperti fibrilasi ventrikel tanpa denyut nadi. Suntikan.
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Amiodarone injection side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.. Amiodarone takes a long time to completely clear from your body. You may continue to have side effects from amiodarone after you stop using it.
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Selama atau setelah pemberian terapi amiodarone intravena, individu dapat dialihkan ke terapi amiodarone oral. Berikut dosis konversi oral dari amiodarone pada individu yang telah mendapatkan amiodarone intravena: Kurang dari 1 minggu infus IV: 800-1600 mg/ hari. 1-3 minggu infus IV: 600-800 mg/ hari. Lebih dari 3 minggu infus IV: 400 mg/ hari.