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Drug-Induced Hypersensitivity Syndrome (DIHS) is a severe and rare systemic reaction triggered by a drug (usually an antiepileptic drug). We present a case of DISH and we review studies on the clinical features and treatment of DIHS, and on its pathogenesis.
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ECOSYSTEM. DIH4INDUSTRY Ecosystem not only includes the Manufacturing DIHs in the relevant focus areas of H2020 DT-ICT workprogramme (SMART and EMBEDDED SYSTEMS, Robotics, Manufacturing I4MS, Photonics and Big Data DIHs projects), but also encompasses DIHs with a technological specialisation in Industrial IoT and Industrial AI, as well as a.
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Introduction. Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) is a severe adverse drug reaction classically associated with multiorgan involvement and often complicated by herpesvirus reactivation. 1 Mortality, dependent on patient age, underlying comorbidities, and the drug involved, occurs in up to 10% of patients and is typically.
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Drug-induced hypersensitivity syndrome (DIHS), also called drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, is a potentially fatal drug-induced hypersensitivity reaction that is characterized by a cutaneous eruption, multiorgan involvement, viral reactivation, and hematologic abnormalities.
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Drug-induced hypersensitivity syndrome (DIHS), including Stevens-Johnson syndrome (SJS), is a severe rash that often develops 2-6 weeks after the intake of the causative drug; however, its diagnosis is sometimes difficult. This article describes a case in which a patient with DIHS-induced multiple organ failure was successfully treated with blood purification therapy.
DrugInduced Hypersensitivity Syndrome (DIHS)/Drug Reaction With
Summary. Drug rash with eosinophilia and systemic symptoms, or DRESS syndrome, is a severe hypersensitivity reaction to certain medications. Symptoms of the condition include skin eruption, fever.
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Drug reaction with eosinophilia and systemic symptoms/drug-induced hypersensitivity syndrome (DIHS/DRESS) is one example of a severe delayed T-cell mediated adverse drug reaction. DIHS/DRESS presents with fever, widespread rash and facial edema, organ.
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INTRODUCTION. Drug-induced hypersensitivity syndrome (DIHS) was described in 1950 by Chaiken et al, 15 as the triad of fever, rash, and multiorgan failure occurring 1-8 weeks after an aromatic anticonvulsant drug had been started. Roujeau and colleagues 4,7,71 renamed the syndrome DRESS: drug rash with eosinophilia and systemic symptoms. Organ failure differentiates DIHS from other drug.
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Our understanding of the pathophysiology of DIHS/DRESS has evolved considerably over the last decade. DIHS/DRESS is distinguished from other drug eruptions by several characteristics, including the fact that it is associated with a limited number of causative drugs, exhibits late onset and a prolonged course, and patients' clinical symptoms deteriorate after treatment with the causative drug.
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Drug-induced hypersensitivity syndrome (DIHS) is a life threatening "delayed-type drug allergic response characterized by skin eruptions, fever, and multiorgan involvement." 1 DIHS is.
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Drug reaction with eosinphilia and systemic symptoms (DRESS) and drug-induced hypersensitivity syndrome (DiHS) represent the same spectrum of a drug reaction.To compare the clinical profile of patients diagnosed as definite/probable DRESS by the Registry.
DrugInduced Hypersensitivity Syndrome (DIHS)/Drug Reaction With
Drug-induced hypersensitivity syndrome (DIHS), also called drug rash with eosinophilia and systemic symptoms (DRESS), is a severe reaction usually characterized by fever, rash, and multiorgan failure, occurring 1-8 weeks after drug introduction. It is an immune-mediated reaction involving macrophage and T-lymphocyte activation and cytokine.