Pueraria mirifica extract / puerarin Goutte d’amour
Puerarin, an isoflavone glycoside derived from Pueraria lobata (Willd.) Ohwi, has been identified as a pharmacologically active component with diverse benefits. A large number of experimental and clinical studies have demonstrated that puerarin is widely used in the treatment of a variety of diseases. Among them, cardiovascular diseases (CVDs.
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Puerarin is extensively distributed in numerous organs including the kidney, mammary gland, femur, tibia, stomach, liver, pancreas, brain, and lungs, but at a low rate because of its poor availability. However, when co-administered with compounds like gastrodin that can convey it into the cell, it shows a wide range of pharmacological.
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Puerarin is an isoflavone compound extracted from the root of Pueraria lobata and has pharmacological effects such as dilating cerebral vessels and anti-free radical generation in cerebral ischemic tissues. With the deepening of experimental research and clinical research on puerarin, it has been found that puerarin has a protective effect on.
Puerarin
Puerarin, also called daidzein-8-c-glucoside (7,4'-dihydroxy-8-c-glycosylisoflavone), is an isoflavone compound isolated from Pueraria lobata (Fig. 1).As one of the important flavonoids, puerarin has unique physicochemical properties [33].Due to the stereo-hindrance of C-cyclopyranyl group, puerarin molecules easily form large conjugate systems, which tend to be flat in space, and thus, its.
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Pueraria mirifica extract / puerarin
2.1. Obesity, metabolic syndrome, and diabetes mellitus. Obesity, metabolic syndrome, and diabetes mellitus are major risk factors for the initiation and progression of cardiovascular and cerebrovascular diseases and are dramatically increased with advancing age in modern society. 12 In obese mice treated with puerarin for 8 months, circulating levels of isoflavone metabolites were.
Puerarin—an isoflavone with beneficial effects on bone health
Puerarin is a C-glucoside of the isoflavone daidzein extracted from Pueraria. It has been widely investigated to explore its therapeutic role in eye diseases and the molecular mechanisms. Purpose: To collect the available literature from 2000 to 2022 on puerarin in the treatment of ocular diseases and suggest the future required directions to.
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puerarin. Puerarin is the major bioactive ingredient isolated from the root of the Pueraria lobata (Willd.) Ohwi, which is well known as Gegen (Chinese name) in traditional Chinese medicine. As the most abundant secondary metabolite, puerarin was isolated from Gegen in the late 1950s. Since then, its pharmaco..
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Puerarin has various effects such as vasodilation, cardioprotection, neuroprotection, antioxidant, anticancer, anti-inflammation, alleviating pain, promoting bone formation, inhibiting alcohol.
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Up to now, puerarin has been widely proven to have pharmacological activities such as vasodilator, anti-inflammatory, antioxidant, anti-apoptotic, regulating autophagy, anti-insulin resistance, anti-cancer, etc. It has protective effects on cell damage caused by pathological factors and has shown good efficacy in the treatment of various diseases (Ma et al., 2022).
الرعاية الصحية Puerarin Kudzu الجذر استخراج مسحوق العشبية
1. Introduction. Puerarin is the main active constituent isolated from the root of the Pueraria lobata (Willd.)Ohwi (Fabaceae), which is native to Southeast Asia and widely known as Gegen in traditional Chinese medicine. As one of the earliest known Chinese medicinal herbs in China, Gegen is frequently used to treat a wide range of conditions including fever, pain, diabetes, gastrointestinal.
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Puerarin derivative P1-EA and P2-EA were formed by substitution of the original phenolic hydroxyl in the puerarin molecules, which had higher lipophilicity and thus better permeabilized through the blood-brain barrier as compared to puerarin. It was resulted in an enhancement of protective activity against cerebral ischemic damage in a mouse.
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Puerarin is mainly used to treat eye diseases by ocular administration and systemic administration. Puerarin has poor water and lipid solubility. Its solubility in water is 0.46 mg/ml, and in phosphate buffer at pH 7.4 is 7.56 mg/ml. Therefore, puerarin has poor oral absorption and low bioavailability.
Puerarin reduces ischemia/reperfusioninduced myocardial injury in diabetic rats via
Puerarin has shown unique pharmacological effects on myocardial ischemia (MI). Changing the crystal form is an effective approach to improve the cardioprotective effects of puerarin. However, the.
Puerarin LKT Labs
Puerarin is an isoflavone compound derived from Pueraria lobata in traditional Chinese medicine. Accumulating evidence has indicated that puerarin demonstrates multiple pharmacological effects and exhibits treatment potential for various neurological disorders. Based on the latest research progress.
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Puerarin, a chemotaxonomic marker of Pueraria, received investigational drug status for the treatment of alcohol abuse and listed in DRUGBANK database. The purpose of this review is to provide insights on health benefits of Pueraria, its bioactive constituents and molecular mechanisms. The information is retrieved from various databases.