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Diazepam is a medication that belongs to the class of benzodiazepines, which are used to treat anxiety, seizures, muscle spasms, and other conditions. Learn how to use diazepam safely and.
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Diazepam is mainly metabolised in the liver by CYP2C19 and CYP3A4 to its major active metabolite, desmethyldiazepam, and two minor active metabolites, temazepam and oxazepam. According to a study, approx 3% of Caucasians and 15-20% of Asians are poor metabolisers of CYP2C19 or have decreased or absent CYP2C19 enzyme activity. Available.
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Diazepam rektal bisa diberikan dalam dosis sebagai berikut: Berat badan >10 kg: dosis 0,5 mg/kg, dapat diulang bila perlu, maksimal 10 mg. Usia 2−5 tahun: dosis inisial 0,5 mg/kg, dibulatkan ke atas sesuai dosis yang tersedia. Usia 6−11 tahun: dosis inisial 0,3 mg/kg, dibulatkan ke atas sesuai dosis yang tersedia.
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Diazepam is a controlled substance drug used to treat anxiety, alcohol withdrawal, muscle spasms, and certain types of seizure. Learn more here.
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Diazepam is used to relieve symptoms of anxiety and alcohol withdrawal. This medicine may also be used to treat certain seizure disorders and help relax muscles or relieve muscle spasm. Diazepam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow.
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confusion, paranoia; or. new or worsening seizures. Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury. Common diazepam side effects may include: drowsiness; feeling tired; muscle weakness; or. problems with balance or muscle movement.
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Kandungan: Diazepam; Kemasan: Dus, 10 Ampul @ 2 ml; Produksi: Sanbe Farma; Harga Valisanbe Injeksi: Rp. 16.000 - Rp. 22.000/ampul; Kegunaan Valisanbe. Obat valisanbe digunakan untuk premedikasi atau pemeliharaan dan pemulihan anestesi serta untuk memberikan efek tenang dalam prosedur bedah dan medis minor.
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Berikut ini adalah dosis diazepam bentuk enema sesuai tujuan penggunaannya: Tujuan: Membantu meredakan kejang. Dewasa: 0,5 mg/kgBB, dosis dapat diulang tiap 12 jam. Dosis maksimal 30 mg. Anak-anak: Untuk anak usia 2-5 tahun, dosisnya 0,5 mg/kgBB, sedangkan untuk anak usia 6-11 tahun, dosisnya 0,3 mg/kgBB.
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In contrast, only α1 (V279A) enhances the efficiency of DZ-to-pore linkage, whereas mutations in the other two subunits have no effect. These observations show that the central residue in the M2-M3 linkers of distinct subunits in synaptic α1β2γ2 GABA A Rs contribute asymmetrically to the intrinsic closed-open equilibrium and its modulation.
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Diazepam is a benzodiazepine medication that is FDA approved for the management of anxiety disorders, short-term relief of anxiety symptoms, spasticity associated with upper motor neuron disorders, adjunct therapy for muscle spasms, preoperative anxiety relief, management of certain refractory epilepsy patients, and adjunct in severe recurrent convulsive seizures, and an adjunct in status.
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Valium (diazepam) is used for the short-term treatment of anxiety and seizure disorders. Diazepam is thought to work by enhancing the effects of GABA, which is an inhibitory neurotransmitter in the central nervous system. Valium belongs to the class of medicines known as benzodiazepines. 2. Upsides.
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confusion, paranoia; or. new or worsening seizures. Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury. Common Valium side effects may include: drowsiness; feeling tired; muscle weakness; or. problems with balance or muscle movement.
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Absorption. After oral administration, it is considered that diazepam is rapidly and completely absorbed from the gastrointestinal tract as >90% of diazepam is absorbed and the average time to achieve peak plasma concentrations is 1 - 1.5 hours with a range of 0.25 to 2.5 hours 15,16,6.. Absorption is delayed and decreased when administered with a moderate fat meal 15.
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BRAND NAME(S): Valium. Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage. USES: Diazepam is used to treat anxiety and muscle spasms.The injection form is used when the medication cannot be taken by mouth. It is also used in patients with alcohol withdrawal to prevent seizures and treat other symptoms (e.g., agitation.
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Diazepam termasuk dalam golongan obat psikotropika sehingga hanya bisa didapatkan dan digunakan berdasarkan resep dokter. Tujuan: meredakan kecemasan. Bentuk: tablet. Anak: 1-2,5 mg/hari. Dosis dapat dinaikkan secara perlahan jika diperlukan. Dewasa: diberikan dosis 2 mg, tiga kali sehari.
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Hepatic; diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the active metabolite temazepam.. Rectal: Undiluted 5 mg/mL parenteral formulation (filter if using ampul): Infants, Children, and Adolescents: 0.5 mg/kg/dose then 0.25 mg/kg/dose in 10 minutes if needed.